Institute of Histology and Embryology, Faculty of Medicine
Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal
Phone: 351 21 7934340, Fax: 351 21 7951780

Education

• 1977-1983 MD, Faculty of Medicine, University of Lisbon (classification 18/20)
• 1988 PhD, Faculty of Medicine, University of Lisbon (with honours)
• 1997 Agregação, Faculty of Medicine, University of Lisbon.

• 1989-1992 Post-doctoral fellow, European Molecular Biology Laboratory, Heidelberg, Germany
• 1993-1998 Associate Professor, Faculty of Medicine, University of Lisbon
• 1996-present Acting Head of Division of Cell and Molecular Biology, Biomedical Research Center (CEBIP), University of Lisbon.
• 1998 Appointment to Full Professor, Faculty of Medicine, University of Lisbon
• 2001-present Executive Coordinator, Institute of Molecular Medicine, University of Lisbon

• 1981 First Pfizer Prize, Sociedade das Ciências Médicas, Lisboa.
• 1989 First Pfizer Prize, Sociedade das Ciências Médicas, Lisboa.
• 1989-1991 EMBO post-doctoral fellowship
• 1993 José Sala-Trepat Prize, Fondation de France/Institut Pasteur, Paris
• 1994 Elected EMBO member
• 1999 Member of Academia Portuguesa de Medicina
• 2000 Member of Academia das Ciências de Lisboa
• 2001 Comenda Ordem de Santiago de Espada

• 1994-present Member of the Editorial Advisory Board of the International Journal of Developmental Biology
• 1994-present Scientific reviewer for the following journals: EMBO Journal; Nature Cell Biology; Journal of Cell Biology; Trends in Cell Biology; Journal of Cell Science; European Journal of Cell Biology; Experimental Cell Research; Chromosoma 1995-present Evaluator for fellowships and grants, Junta Nacional de Investigação Científica e Tecnológica/Fundação para a Ciência e Tecnologia (Portugal)
• 1997-present Evaluator for Research Networks (European Union)
• 1998 Member of the Advisory Committee for Research into Genomes in Europe (European Union)
• 1998-present Member of the Advisory Branch for ELSO 2000 (European Life Scientist Organization)
• 1998-present Member of the Scientific Advisory Board for The Institute of Molecular Pathology (IPATIMUP), University of Porto, Portugal.
• 2000 Evaluator for Research Grants (The Wellcome Trust; Human Frontier Science Program)
• 2001 Member of the Selection Committee for The EMBO Young Investigator Program

Metabolism of RNA in the nucleus of higher eukaryots. The role of nuclear structure in transcription, processing and transport of messenger RNA. Regulation of alternative splicing. RNA diseases. Gene expression in 4 dimensions. Macromolecules in motion inside the living cell. RNOMICS: An integrated analysis of links between pathways of RNA metabolism in the post-genomic era.

1. Calapez, A., Pereira, H.M., Calado, A., Braga, J., Rino, J., Carvalho, C., Tavanez, J.P., Wahle, E., Rosa, A.C. and Carmo-Fonseca, M. (2002)
   The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive.
   J. Cell Biol. 159, 795-805.
2. Carmo-Fonseca, M. (2002)
   The contribution of nuclear compartmentalization to gene regulation.
   Cell 108, 513-521.
3. Muhlemann, O., Mock-Casagrande, C.S., Wang, J., Li, S., Custodio, N., Carmo-Fonseca, M., Wilkinson, M.F. and Moore, M.J. (2001)
   Precursor RNAs harboring nonsense codons accumulate near the site of transcription.
   Mol. Cell 8, 33-43.
4. Rodrigues, J.P., Rode, M., Gatfield, D., Blencowe, B.J., Carmo-Fonseca, M. and Izaurralde, E. (2001)
   REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus.
   Proc. Natl. Acad. Sci. USA 98, 1030-1035.
5. von Kobbe, C., van Deursen, J.M., Rodrigues, J.P., Sitterlin, D., Bachi, A., Wu, X., Wilm, M., Carmo-Fonseca, M. and Izaurralde, E. (2000)
   Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98.
   Mol. Cell 6, 1243-1252.
6. Carmo-Fonseca, M., Mendes-Soares, L. and Campos, I. (2000)
   To be or not to be in the nucleolus.
   Nature Cell Biol. 2, E107-E112.